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A severe epilepsy syndrome with triad of infantile spasms, an interictal electroencephalogram (EEG) pattern termed hypsarrhythmia, and mental retardation.
Reports on the use of topiramate for treatment of infantilespasms are limited.
2
Seizure types were variable, including infantilespasms and myoclonic seizures, and often prolonged.
3
Twelve patients had symptomatic infantilespasms, and two patients had cryptogenic infantilespasms.
4
This study evaluated the efficacy and safety of vigabatrin for Japanese patients with infantilespasms.
5
We encountered two WBS patients presenting with infantilespasms, which is extremely rare in WBS.
6
The male infant presented with tonic seizures in early infancy and subsequently developed infantilespasms.
7
Comparisons were made to recordings from infantilespasms patients.
8
Vigabatrin was deemed to be clinically effective and well tolerated in Japanese patients with infantilespasms.
9
We prospectively followed 15 children with recently diagnosed infantilespasms treated with topiramate for efficacy and tolerability.
10
Infantilespasms were reported in 10% of the probands.
11
Then, at about six months old, "he stopped responding and started to have infantilespasms".
12
Results: Twenty children had partial seizures; two had infantilespasms; and one had generalized tonic-clonic seizures at onset.
13
Conclusions: PLP could replace PN in the treatment of intractable childhood epilepsy, particularly in the treatment of infantilespasms.
14
The child suffered from a rare disorder called infantilespasms, which could lead to seizures, cerebral palsy and autism.
15
In patients with infantilespasms and severe developmental delay PEHO syndrome should be considered; it is not confined to Finnish heritage.
16
Recordings also revealed a ramp-up in the number of neocortical slow oscillations preceding spasms, which was also observed in infantilespasms patients.